ABSTRACT
Background : Diabetic patients need to consume multiple Vmedications at a time due to presence of Hyperglycemia, its pathophysiology and complications.In this context the compliance of the patient depends on the cost of therapy, The conduction of this study was faced with limitations like the COVID-19 pandemic. In spite of that, we have decided to conduct this challenging task by analyzing the pattern of prescriptions and comparing the prices of Anti-diabetic Drugs in our Tertiary Care Teaching Hospital. Objective : • To study the pattern of prescription writing in Type II Diabetes Mellitus and its association with the extent of control of the disease. • To analyze and compare the cost of different Anti-diabetic Drugs in Type II Diabetes Mellitus in a Tertiary Care Hospital. Material and Methods : This is an observational study of descriptive type. It is prospective in nature. All the demographic characteristics of the patient, disease profile, drug profile and prescription profile were included in the case report form. A photocopy of the patient’s Pharmacy Bill was collected from the indoor Pharmacy for analysis. Result : The mean number of anti-diabetic medications prescribed in Generic name was 3.0(±2.12) while the mean number of drugs prescribed in Brand name was 4.02(±1.99). The average number of prescribed injectable drugs was 0.11 (±0.31) with p- value=0.012 and the mean number of prescribed Fixed Dose Combinations (FDCs) was 0.16 (±0.42) with p-value=0.005. The total number of prescribed Anti-diabetic medications was higher in presently Hyperglycemic patients under Anti-diabetic Therapy compared to presently Normoglycemic patients under Anti-diabetic Therapy. A weak positive correlation was found between family income per capita and total cost of treatment. Conclusion: The total cost of treatment in presently Hyperglycemic patients under Anti-diabetic Therapy is relatively high due to prescription of more number of Anti-diabetic Medications. Metformin is the most common Anti-diabetic agent used in clinical practice and oral route of Drug Administration is mostly preferred in the OPD settings.